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Publications at HKU

2024

Cobalt-Catalyzed Desymmetrization of Malononitriles via Enantioselective Borohydride Reduction

Zheng, Yin;^ Yang, T.;^ Chan, K. F.; Lin, Z.*; Huang, Z.*, Nat. Chem. 2024, 16, [link]

(^ equal contribution)

2024 Nat Chem Zheng Yin

2023

Modular and Diverse Synthesis of Amino Acids via Asymmetric Decarboxylative Protonation of Aminomalonic Acids

Zheng, Wei-Feng; Chen, J. (UG); Qi, X.*; Huang, Z.*, Nat. Chem. 2023, 15, 1672. [link]

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  • Highlighted by X. Lin and A. G. Woldegiorgis in Nature Chemistry, 'An acid for an acid'

  • Highlighted by R. Xu, and B. List in Synfacts.

Zinc-Catalyzed Desymmetric Hydrosilylation of Monosubstituted Malonic Esters

Zhang, Yixiao; Xu, P.; Zhao, Q.; Wang, J. ; Huang, Z.*, Org. Chem. Front. 2023, 10, 1675. [Link]

(invited article for emerging investigator series)

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2023 OCF Zhang Yixiao

2022

Diverse Synthesis of α-Tertiary Amines and Tertiary Alcohols via Desymmetric Reduction of Malonic Esters

Liu, Haichao; Lau, H. M.; Xu, P.; Chan, T. H. (UG); Huang, Z.*, Nat. Commun. 2022, 13, 4759. [Link]

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  • Highlighted by H. Yamamoto, and T. Hattori in Synfacts.

Desymmetric Cyanosilylation of Acyclic 1,3-Diketones

Xu, Pan; Shen, C.; Xu, A.; Low, K.-H.; Huang, Z.*, Angew. Chem. Int. Ed. 2022, 61. e202208443. [Link]

Pan Xu
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Desymmetric Partial Reduction of Malonic Esters

Xu, Pengwei; Liu, S.; Huang, Z.*, J. Am. Chem. Soc. 2022, 144​, 6918-6927. [Link]

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2022 JACS Xu Pengwei
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A Unified and Desymmetric Approach to Chiral Tertiary Alkyl Halides

Zheng, Yin; Zhang, S. (UG); Low, K.-H.; Zi, W.; Huang, Z.*, J. Am. Chem. Soc. 2022, 144, 1951-1961. [Link]

Zheng Yin
2022 JACS Zheng Yin
  • Highlighted by M. Oestreich, H. F. T. Klare, and N. Kranidiotis-Hisatomi in Synfacts.

Sewing Molecules Together with Light

Xu, Pan; Huang, Z.*, Trends Chem. 2022, 4, 169-171 (invited Spotlight). [Link]

2021

Catalytic Reductive Desymmetrization of Malonic Esters

Xu, Pengwei; Huang, Z.*, Nat. Chem. 2021, 13, 634-642. [Link]

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The Huang Group at HKU

香港大学黄重行课题组

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