Publications at HKU


Catalytic Reductive Desymmetrization of Malonic Esters

Xu, P.; Huang, Z.*, Nat. Chem. 2021, 13, 634. [Link]

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  • Highlighted by J. Gajewy and M. Kwit in Nature Chemistry, 'The gains from breaking symmetry'

  • Highlighted by L. Boerner in C&EN News, 'Reduction carves path to chiral compounds'

  • Highlighted by G. R. Stephenson in Chemistry&Industry. 

  • Featured in X-mol

Selected Publications before HKU

Total Synthesis of Bryostatin 3

Trost, B. M.*; Wang, Y.; Buckl, A. K.; Huang, Z.; Nguyen, M. H.; Kuzmina, O., Science 2020, 368, 1007. [Link]

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Catalytic (3+2) Palladium‐Aminoallyl Cycloaddition with Conjugated Dienes

Trost, B. M.*; Huang, Z., Angew. Chem. Int. Ed. 2019, 58, 6396. [Link]

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Catalytic Palladium-Oxyallyl Cycloaddition

Trost, B. M.*; Huang, Z.; Murhade, G. M., Science 2018, 362, 564. [Link]

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Palladium-Catalyzed Redox Cascade for Direct β-Arylation of Ketones

Huang, Z.; Dong, G.*, Tetrahedron 2018, 74, 3253. [Link]

Site-Selectivity Control in Organic Reactions: A Quest to Differentiate Reactivity among the Same Kind of Functional Groups

Huang, Z.; Dong, G.*, Acc. Chem. Res. 2017, 50, 465. [Link]

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A Hydrazone-Based Directing Group Strategy for β-C−H Oxidation of Aliphatic Amines

Huang, Z.; Wang, C.; Dong, G.*, Angew. Chem. Int. Ed. 2016, 55, 5209. [Link]

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Transition Metal-Catalyzed Ketone-Directed or Mediated C−H Functionalization

Huang, Z.; Lim, H. N.; Mo, F.; Young, M.; Dong, G.*, Chem. Soc. Rev. 2015, 44, 7764. [Link]


Palladium-Catalyzed Direct β-Arylation of Ketones with Diaryliodonium Salts: a Stoichiometric Heavy Metal-Free and User-Friendly Approach

Huang, Z.; Sam, Q. P.; Dong, G.*, Chem. Sci. 2015, 6, 5491. [Link]

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Catalytic C−C Bond Forming Transformations via Direct β-C−H Functionalization of Carbonyl Compounds

Huang, Z.; Dong, G.*, Tetrahedron Lett. 2014, 55, 5869. [Link]

Catalytic Direct β-Arylation of Simple Ketones with Aryl Iodides

Huang, Z.; Dong, G.*, J. Am. Chem. Soc. 2013, 135, 17747. [Link]

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Auto-Tandem Catalysis: Synthesis of Acridines by Pd-Catalyzed C=C Bond Formation and C(sp2)−N Cross-Coupling

Huang, Z.; Yang, Y.; Xiao, Q.; Zhang, Y.*; Wang, J.*, Eur. J. Org. Chem. 2012, 6586. [Link]

The Huang Group at HKU